potassium chloride classification and actionpandas filter columns by name

at the low end of the dosing range because of the potential for development of hyperkalemia Modify Therapy/Monitor Closely. Minor/Significance Unknown. Monitor Closely (1)potassium chloride increases and indapamide decreases serum potassium. Interaction especially seen in the treatment of hypokalemia. Effect of interaction is not clear, use caution. Visit the FDA MedWatch website or call 1-800-FDA-1088. Potassium chloride extended-release capsules are sufficient numbers of subjects aged 65 and over to determine whether they Effect of interaction is not clear, use caution. Serious - Use Alternative (1)potassium acid phosphate and potassium chloride both increase serum potassium. Each formulation is available only by prescription. 2013 Sep; [PubMed PMID: 23964767], Gennari FJ,Weise WJ, Acid-base disturbances in gastrointestinal disease. potassium chloride increases effects of insulin glargine by pharmacodynamic synergism. Patients with other cardiac disorders, such as heart failure or AV block, also require close monitoring when receiving potassium supplements. Monitor Closely (1)potassium chloride increases and metaproterenol decreases serum potassium. potassium chloride decreases levels of rilpivirine by increasing gastric pH. olmesartan and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. American family physician. Monitor Closely (1)potassium chloride increases and bendroflumethiazide decreases serum potassium. Minor (1)potassium chloride increases effects of chlorpropamide by pharmacodynamic synergism. potassium chloride increases and epinephrine racemic decreases serum potassium. [4][5], Hyperaldosteronism: Aldosterone is a mineralocorticoid that signals renal collecting duct cells to both retain sodium and water and secrete potassium and hydrogen ions. hyperkalemia can result. In the U.S. Effect of interaction is not clear, use caution. potassium chloride will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Use Caution/Monitor. Modify Therapy/Monitor Closely. has not identified differences in responses between the elderly and younger patients. [, Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Interaction especially seen in the treatment of hypokalemia. insufficient. Because elderly patients are more likely to have Minor/Significance Unknown. DOSAGE AND ADMINISTRATION]. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Replaces potassium levels when low, also maintain potassium levels. Modify Therapy/Monitor Closely. Monitor Closely (1)potassium chloride increases and epinephrine racemic decreases serum potassium. in the USP, with a child-resistant closure. Monitor Closely (1)esmolol and potassium chloride both increase serum potassium. HOW TO USE: To prevent stomach upset, you must first mix your dose of potassium with a glass (4 to 8 ounces/120 to 240 milliliters) of cold water or juice as directed by your doctor. potassium chloride increases effects of tolbutamide by pharmacodynamic synergism. Monitor Closely (1)timolol and potassium chloride both increase serum potassium. potassium chloride increases and methyclothiazide decreases serum potassium. Modify Therapy/Monitor Closely. Generic:- Store in a cool, dry placeCena K :- Protect from light- Store at 77 degrees F; excursions permitted to 59-86 degrees FEffer-K:- Store at room temperature (between 59 to 86 degrees F)Epiklor:- Protect from light- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FK Plus:- Protect from light- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FK Plus Care ET :- Store at room temperature (between 59 to 86 degrees F)Kaon-CL:- Protect from freezing- Store at controlled room temperature (between 68 and 77 degrees F)Kay Ciel :- Protect from light- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FK-Dur:- Store at 77 degrees F; excursions permitted to 59-86 degrees FK-Lor:- Protect from light- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FKlor-Con:- Store at controlled room temperature (between 68 and 77 degrees F)Klor-Con EF:- Store at room temperature (between 59 to 86 degrees F)Klor-Con M10:- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FKlor-Con M15:- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FKlor-Con M20:- Store at 77 degrees F; excursions permitted to 59-86 degrees FKlotrix:- Store at controlled room temperature (between 68 and 77 degrees F)K-Lyte:- Store at room temperature (between 59 to 86 degrees F)K-Sol :- Protect from light- Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FK-Tab:- Store at controlled room temperature (between 68 and 77 degrees F)K-Vescent :- Store at room temperature (between 59 to 86 degrees F)Micro-K:- Store at controlled room temperature (between 68 and 77 degrees F)Micro-K Extencaps:- Store at controlled room temperature (between 68 and 77 degrees F)Slow-K:- Protect from light- Protect from moisture- Store at controlled room temperature (between 68 and 77 degrees F). Monitor Closely (1)perindopril increases levels of potassium chloride by decreasing elimination. Use Caution/Monitor. compression of the esophagus. Minor/Significance Unknown. Regardless of the cause, hypokalemia is a significant clinical derangement to address due to the increased risk of life-threatening cardiac arrhythmias. Monitor Closely (1)aspirin rectal and potassium chloride both increase serum potassium. Clinical journal of the American Society of Nephrology : CJASN. More information is availablein the FDAs database for current drug labels. Epub 2005 Aug 10. Potassium chloride is a medication used in the management and treatment of hypokalemia. Modify Therapy/Monitor Closely. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. esmolol and potassium chloride both increase serum potassium. [, Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Interaction especially seen in the treatment of hypokalemia. Monitor Closely (1)meloxicam and potassium chloride both increase serum potassium. [, Tornberg J, Segerstrale M, Kulesskaya N, Voikar V, Taira T, Airaksinen MS: KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)ketorolac intranasal and potassium chloride both increase serum potassium. any unabsorbed drug. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. 1997 Jul; [PubMed PMID: 9219169], Lee FT,Elaraj D, Evaluation and Management of Primary Hyperaldosteronism. If serum potassium concentration is <2.5 mEq/L, use Use potassium gluconate during pregnancy only if the potential benefit justifies the potential risk to the fetus. Potassium chloride: The risk or severity of gastrointestinal ulceration can be increased when Promethazine is combined with Potassium chloride. Potassium citrate: Potassium citrate may increase the excretion rate of Promethazine which could result in a lower serum level and potentially a reduction in efficacy. Use Caution/Monitor. Effect of interaction is not clear, use caution. ketorolac and potassium chloride both increase serum potassium. The membrane gradient is responsible for the resting transmembrane electric potential, primarily determined by the diffusion of potassium out of the cell. For example, consumption of glycyrrhizin in licorice can lead to apparent mineralocorticoid excess due to inhibition of 11-hydroxysteroid dehydrogenase type 2. with diarrhea and malnutrition from birth to 18 years. Modify Therapy/Monitor Closely. Hyperkalemia is usually asymptomatic and may be Rougier Pharma Division Of Ratiopharm Inc, Bristol Labs Division Of Bristol Myers Squibb, Ncs Health Care Of Ky, Inc Dba Vangard Labs, POTASSIUM CHLORIDE INJECTION - HIGHLY CONCENTRATED (100 mEq/l), POTASSIUM CHLORIDE INJECTION - HIGHLY CONCENTRATED (200 mEq/l), POTASSIUM CHLORIDE INJECTION - HIGHLY CONCENTRATED (400 mEq/l), (20 Mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP, (20 Mmol/l) Potassium Chloride In 5% Dextrose and 0.9% Sodium Chloride Injection USP, (20 Mmol/l) Potassium Chloride In 5% Dextrose Injection USP, (20mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP, (20mmol/l) Potassium Chloride In 5% Dextrose and 0.2% Sodium Chloride Injection USP, (20mmol/l) Potassium Chloride In 5% Dextrose and 0.45% Sodium Chloride Injection USP, (40 Mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USP, (40 Mmol/l) Potassium Chloride In 5% Dextrose Injection USP, (40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USP, (40mmol/l) Potassium Chloride In 3.3% Dextrose and 0.3% Sodium Chloride Injection USP, BIOFLEKS %5 DEKSTROZ RINGER LAKTAT 500 ML SOLUSYON (PVC TORBA) SETSIZ, BIOFLEKS %5 DEKSTROZ RINGER LAKTAT ENJEKTABL SOL (PVC TORBA) 1000 ML SETLI, BIOFLEKS %5 DEKSTROZ RINGER LAKTAT ENJEKTABL SOL (PVC TORBA) 1000 ML SETSIZ, BIOFLEKS %5 DEKSTROZ RINGER LAKTAT ENJEKTABL SOL (PVC TORBA) 500 ML SETLI, BIOFLEKS 10 MEQ/L POTASYUM KLORUR %5 DEKSTROZ SOLUSYONU 1000 ML SETLI, BIOFLEKS 10 MEQ/L POTASYUM KLORUR %5 DEKSTROZ SOLUSYONU 1000 ML SETSIZ, BIOFLEKS 10 MEQ/L POTASYUM KLORUR %5 DEKSTROZ SOLUSYONU 500 ML SETLI, BIOFLEKS 10 MEQ/L POTASYUM KLORUR %5 DEKSTROZ SOLUSYONU 500 ML SETSIZ, BIOFLEKS 20MEQ/L KCL%5DEK 100 ML SOLUSYON SETSIZ, BIOFLEKS 20MEQ/L KCL%5DEK 1000 ML SOLUSYON SETSIZ, Kit; powder, for solution; tablet, delayed release, Cream; kit; liquid; ointment; tablet; tablet, chewable; tablet, film coated, Extracorporeal; Intrabiliary; Intracardiac, Klor-Con M20 20meq Controlled Release Tabs, Potassium Chloride Crys CR 20meq Controlled Release Tabs, Potassium Chloride Crys CR 10meq Controlled Release Tabs, Potassium Chloride CR 10meq Controlled Release Tabs, Potassium Chloride CR 8meq Controlled Release Tabs, Micro-K Extencaps 8 meq Sustained-Release Capsule, Potassium Chloride 40 Meq/15ml(20%) Liquid, Potassium Chloride 20 Meq/15ml(10%) Liquid, Pms - Potassium Chloride 1.33 meq/ml Liquid. Relatively high intracellular potassium concentrations leads to passive diffusion out of the cell. Monitor Closely (1)propranolol and potassium chloride both increase serum potassium. For more information, ask your doctor or pharmacist. A normal level of potassium in the blood is important. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. This drug is available at a higher level co-pay. Modify Therapy/Monitor Closely. Monitor Closely (1)diflunisal and potassium chloride both increase serum potassium. Monitor Closely (1)penbutolol and potassium chloride both increase serum potassium. Store at 20-25C (68-77F); excursions are permitted to Use potassium supplements with caution in patients with potassium-aggravated skeletal muscle channelopathy, such as hyperkalemic periodic paralysis, paramyotonia congenita, and potassium-aggravated myotonia/paramyotonia. Such depletion usually develops as a consequence of therapy with diuretics, primarily or secondary hyperaldosteronism, diabetic ketoacidosis, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. atenolol and potassium chloride both increase serum potassium. However, if excretory mechanisms are impaired, of if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result. Potassium ions participate in a number of essential physiological processes, including the maintenance of intracellular tonicity; the transmission . Minor (1)potassium chloride increases effects of repaglinide by pharmacodynamic synergism. Coadministration of antacids with rilpivirine may cause significant decreases in rilpivirine plasma concentrations because of increased gastric pH. Modify Therapy/Monitor Closely. Potassium chloride may increase the hyperkalemic activities of Acebutolol. [23][24], Given the narrow normal range of serum potassium, careful monitoring is a requirement when utilizing KCl. Drug created at June 13, 2005 13:24 / Updated at December 07, 2022 06:22, Structured drug data for data science & ML, Clinical intelligence tool for your software, Search for drug interactions with our API, Get drug allergy and cross sensitivities info. bisoprolol and potassium chloride both increase serum potassium. Effect of interaction is not clear, use caution. magnesium, sodium, chloride, phosphate, and calcium, electrocardiograms and the pain, burning, bruising, swelling, irritation, or skin changes where the medicine was injected. 2018 Apr; [PubMed PMID: 29540487], Ben Salem C,Badreddine A,Fathallah N,Slim R,Hmouda H, Drug-induced hyperkalemia. Tolerable upper limit not established; usual Max dose as a dietary supplement is 2 tablets/day PO. Based on publish literature, the baseline corrected serum Effect of interaction is not clear, use caution. chloride extended-release capsules during pregnancy and animal reproductive chewing and followed with a glass of water or juice to ensure complete swallowing However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. 7447-40-7 100 Not classified Full text of hazard classes and H-statements : see section 16 3.2. Minor/Significance Unknown. To view formulary information first create a list of plans. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. 1 to 2 tablets PO daily. MISSED DOSE: If you miss a dose, take it as soon as you remember. Treatment of hypokalemia: The recommended initial As hypokalemia can result from insulin treatment, the clinician can administer KCl to maintain an adequate serum potassium level. Alkalinizing AgentsCarbohydrate IV Solutions and Additives, more than 10%Electrolytes with Carbohydrate SolutionsPotassium SupplementsSodium Chloride Solutions with PotassiumSupplemental Dietary Agents, Potassium is primary intracellular cationDietary supplement used to maintain potassium balance (i.e., hypokalemia prevention)Guidelines recommend that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias, Cena K, Effer-K, Epiklor, K Plus, K Plus Care ET, K-Dur, K-Lor, K-Lyte, K-Sol, K-Tab, K-Vescent, Kaon-CL, Kay Ciel, Klor-Con, Klor-Con EF, Klor-Con M10, Klor-Con M15, Klor-Con M20, Klotrix, Micro-K, Micro-K Extencaps, Slow-K, Cena K/Kaon-CL/Kay Ciel/K-Sol/Potassium Chloride Oral Sol: 15mL, 20mEq, 40mEqEffer-K/K Plus Care ET/Klor-Con EF/K-Lyte/K-Vescent/Potassium Bicarbonate/Potassium Bicarbonate, Potassium Chloride Oral Tab Effrv: 25mEq, 10-0.84g, 20-1.68g, 25-1.5gEpiklor/K Plus/Kay Ciel/K-Lor/Klor-Con/K-Sol/Potassium Chloride Oral Pwd F/Recon: 20mEq, 25mEqK-Dur/Klor-Con/Klor-Con M10/Klor-Con M15/Klor-Con M20/Klotrix/K-Tab/Potassium Chloride/Slow-K Oral Tab ER: 8mEq, 10mEq, 15mEq, 20mEqKlor-Con/Micro-K/Micro-K Extencaps/Potassium Chloride Oral Cap ER: 8mEq, 10mEqPotassium Acetate/Potassium Chloride/Potassium Chloride, Dextrose/Potassium Chloride, Dextrose, Sodium Chloride/Potassium Chloride, Sodium Chloride Intravenous Inj Sol: 1mL, 2mEq, 4mEq, 10mEq, 20mEq, 30mEq, 40mEq, 50mL, 100mL, 10-5-0.225%, 10-5-0.45%, 20-0.45%, 20-0.9%, 20-5%, 20-5-0.2%, 20-5-0.225%, 20-5-0.3%, 20-5-0.45%, 20-5-0.9%, 30-5%, 30-5-0.225%, 30-5-0.45%, 40-0.9%, 40-5%, 40-5-0.225%, 40-5-0.45%, 40-5-0.9%Potassium Oral Tab: 83mg, 99mg. potassium chloride increases effects of insulin glulisine by pharmacodynamic synergism. Potassium chloride extended-release capsules contain 600 Clinical practice guidelines recommend that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias to minimize complications of potassium depletion. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Nurses can monitor minute-to-minute vital signs and correlate them with symptom development. Risk of hyperkalemia.potassium chloride and benazepril both increase serum potassium. Monitor Closely (1)lisinopril increases levels of potassium chloride by decreasing elimination. Exp Eye Res. Exp Eye Res. Monitor Closely (1)eprosartan and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. Epub 2006 Jun 28. Monitor Closely (1)potassium chloride increases and salmeterol decreases serum potassium. potassium chloride increases and bendroflumethiazide decreases serum potassium. Use Caution/Monitor. potassium chloride increases and indapamide decreases serum potassium. inhibitors or nonsteroidal anti-inflammatory drugs, should usually be started general population, the estimated background risk of major birth defects and potassium chloride increases effects of glipizide by pharmacodynamic synergism. Avoid or Use Alternate Drug. Monitor Closely (1)flurbiprofen and potassium chloride both increase serum potassium. Monitor Closely (1)potassium chloride increases and epinephrine decreases serum potassium. . Monitor Closely (1)tolfenamic acid and potassium chloride both increase serum potassium. Minor (1)potassium chloride increases effects of metformin by pharmacodynamic synergism. Use Caution/Monitor. ibuprofen and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. Solid oral dosage forms of potassium chloride can produce Potassium Chloride in Sodium Chloride Injection, USP is a sterile, nonpyrogenic, solution for fluid and electrolyte replenishment in a single dose container for intravenous administration. The NDC Code 60687-708-09 is assigned to a package of 80 blister pack in 1 carton > 1 tablet, extended release in 1 blister pack (60687-708-11) of Potassium Chloride, a human prescription drug labeled by American Health Packaging. potassium chloride increases toxicity of captopril by Mechanism: unspecified interaction mechanism. (See also Overdose section. Potassium Chloride Safety Data Sheet according to Federal Register / Vol. Use Caution/Monitor. It has a molecular mass of 74.55. Modify Therapy/Monitor Closely. This reduces gastrointestinal irritation. Minor/Significance Unknown. Compare formulary status to other drugs in the same class. Monitor Closely (1)quinapril increases levels of potassium chloride by decreasing elimination. Minor (1)potassium chloride increases effects of insulin detemir by pharmacodynamic synergism. K-LORbelongs to a class of drugs called Electrolyte Supplements, Parenteral; Electrolytes. extended-release capsules and consider possibility of ulceration, obstruction or Monitor Closely (1)potassium chloride decreases levels of rilpivirine by increasing gastric pH. Monitor Closely (1)potassium chloride and potassium citrate/citric acid both increase serum potassium. quinapril increases levels of potassium chloride by decreasing elimination. [, Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. As a component of extracellular fluid, potassium has a normal range of approximately 3.5to 5.0 mEq/L. [15][16][17][18][19], The Food and Drug Administration (FDA) currently approves KCl use in the following formulations: extended-release tablet, extended-release capsule, injectable, oral solution, and powder for oral solution. Applies only to oral form of both agents. Semin Nephrol. Serious - Use Alternative (1)potassium chloride, eplerenone. manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) Monitor Closely (1)naproxen and potassium chloride both increase serum potassium. There are no adequate, well controlled studies with potassium supplements in pregnant women and animal reproduction studies have not been conducted. USES: This medication is a mineral supplement used to treat or prevent low amounts of potassium in the blood. following: In patients who have been stabilized on digitalis, too are nausea, vomiting, flatulence, abdominal pain/discomfort, and diarrhea. 2002 Jan 1;30(1):412-5. Monitor Closely (1)parecoxib and potassium chloride both increase serum potassium. It is odorless and has a saline taste. Any microcapsule/food mixture should The only purpose of the kidneys is to filter blood. Interaction especially seen in the treatment of hypokalemia. The recipient will receive more details and instructions to access this offer. Monitor serum potassium and adjust finerenone dose as described in the prescribing information as necessary. Minor/Significance Unknown. 2. Advise patients seek medical attention if tarry stools or contraindicated in patients on amiloride or triamterene. Excessive mineralocorticoid activity can also occur in aldosterone-independent manners, as well. Modify Therapy/Monitor Closely. AHA 2012 research-highlights slideshow: FREEDOM, TACT, UMPIRE, PHSII, OPERA, FORWARD, LoDoCo, and more, sodium sulfate/magnesium sulfate/potassium chloride. Prevention of Hypokalemia. Monitor Closely (1)sotalol and potassium chloride both increase serum potassium. Chloride (Cl ) has an integral role in buffering action when oxygen and carbon dioxide exchange occurs in the red blood cells. Interaction especially seen in the treatment of hypokalemia. penbutolol and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. containing 10 to 20 units of crystalline, Correct acidosis, if present, with intravenous sodium. Monitor Closely (1)nadolol and potassium chloride both increase serum potassium. potassium chloride increases and gentamicin decreases serum potassium. [, Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. starting at the low end of the dosing range, reflecting the greater frequency Inform patients to take each dose with meals and with a 1990 Mar; [PubMed PMID: 2310280], Kardalas E,Paschou SA,Anagnostis P,Muscogiuri G,Siasos G,Vryonidou A, Hypokalemia: a clinical update. Modify Therapy/Monitor Closely. Minor (1)bisacodyl rectal decreases levels of potassium chloride by inhibition of GI absorption. dietary intake of potassium is 50 to 100 mEq per day. Applies only to oral form of both agents. potassium chloride, eplerenone. Use Caution/Monitor. However, if excretory mechanisms are impaired, potentially fatal Modify Therapy/Monitor Closely. Potassium ions participate in a number of Potassium secretion begins at the distal convoluted tubule. Potassium chloride may increase the hyperkalemic activities of Aceclofenac. potassium chloride and canagliflozin both increase serum potassium. Avoid or Use Alternate Drug. Potassium supplements & Salts. Serious - Use Alternative (1)potassium chloride, oxybutynin. Both drugs increase potassium. Interaction especially seen in the treatment of hypokalemia. This drug is available at a higher level co-pay. ramipril increases levels of potassium chloride by decreasing elimination. perindopril increases levels of potassium chloride by decreasing elimination. Minor/Significance Unknown. If you log out, you will be required to enter your username and password the next time you visit. Potassium is primary intracellular cation Dietary supplement used to maintain potassium balance (i.e., hypokalemia prevention) Guidelines recommend that serum potassium concentrations of at least 4 mEq/L be achieved and maintained in patients with hypertension, heart failure, and cardiac arrhythmias COMMON BRAND NAMES Minor (1)potassium chloride increases effects of insulin aspart by pharmacodynamic synergism. Metabolism: clinical and experimental. Use Caution/Monitor. This activity outlines the indications, action, and contraindications for potassium chloride as a valuable agent in the management and treatment of hypokalemia. 2017 Mar; [PubMed PMID: 28314851], Nardone R,Brigo F,Trinka E, Acute Symptomatic Seizures Caused by Electrolyte Disturbances. 2006 Nov;83(5):1287-94. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and those products formulated for preparation of solution prior to ingestion.1. Potassium chloride extended-release capsules are gastrointestinal bleeding occurs, discontinue potassium chloride Monitor Closely (1)indomethacin and potassium chloride both increase serum potassium. It is in the electrolyte supplement class of medications. Monitor Closely (1)aspirin/citric acid/sodium bicarbonate and potassium chloride both increase serum potassium. Comment: Patients using drugs with extensive anticholinergic effects should avoid concomitant use with solid oral dosage forms of potassium chloride. Potassium Chloride Drug name ( Generic and Trade) Cena-K, Gen-K, K+Care, K+10, K, Potassium Chloride Classification and sub classification Therapeutic- mineral and elect, Potassium Chloride Therapeutic Action Replacement. betaxolol and potassium chloride both increase serum potassium. Applies only to oral form of both agents. You may report side effects to FDA at 1-800-FDA-1088. K-LORmay cause serious side effects including: Get medical help right away, if you have any of the symptoms listed above. Membrane depolarization will occur only when a current is applied to the nerve that exceeds the outward potassium current. Modify Therapy/Monitor Closely. potassium chloride and succinylcholine both increase serum potassium. nabumetone and potassium chloride both increase serum potassium. Monitor Closely (1)piroxicam and potassium chloride both increase serum potassium. Use Caution/Monitor. The background risk for major birth defects and triamterene and potassium chloride both increase serum potassium. Minor/Significance Unknown. Effect of interaction is not clear, use caution. drugs a-z list The risk for cardiac arrhythmia is significant at serum potassium levels greater than 6.0 to 6.5 mEq/L. Monitor Closely (1)nabumetone and potassium chloride both increase serum potassium. The normal potassium ion content of human milk is about 13 mEq/L. Monitor serum potassium and adjust finerenone dose as described in the prescribing information as necessary. commonly, these are "non-preferred" brand drugs or specialty dose is 2 to 4 mEq/kg/day in divided doses. Additive: Aminophylline, amiodarone, Ca gluconate, cimetidine, clindamycin, dobutamine, dopamine, erythromycin, furosemide, heparin, hydrocortisone, lidocaine, norepinephrine, Na bicarb, vancomycin, verapamil, Y-site: Amiodarone, aminophylline, ampicillin, atropine, Ca gluconate, dobutamine, dopamine, epinephrine, esmolol, fentanyl, furosemide, heparin, lidocaine, morphine, norepinephrine, Na bicarb, POTASSIUM SOLUTION/POWDER FOR SOLUTION - ORAL. Coadministration of antacids with rilpivirine may cause significant decreases in rilpivirine plasma concentrations because of increased gastric pH. potassium chloride increases and cyclopenthiazide decreases serum potassium. Modify Therapy/Monitor Closely. [10][11][12][2], Other: During cardiac surgery, KCl serves to induce cardioplegia by interfering with phase 0 of the cardiac action potential. Fluid and electrolyte maintenance therapy, A12BA51 Potassium chloride, combinations, B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS, Blood Substitutes and Perfusion Solutions, Irritable Bowel Syndrome Characterized by Constipation. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Monitor Closely (1)potassium chloride increases and isoproterenol decreases serum potassium. Monitor Closely (1)ibuprofen IV and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. Minor/Significance Unknown. etodolac and potassium chloride both increase serum potassium. Explain the importance of collaboration and communication amongst the interprofessional team to improve outcomes for patients receiving potassium chloride. potassium chloride and digoxin both increase serum potassium. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. 15 to 20C (59-86F) [see USP Controlled Room Temperature.]. Modify Therapy/Monitor Closely. Because these reactions are reported voluntarily Potassium levels below this range, or hypokalemia, broadly result from increased excretion, decreased intake, and increased movement into cells. potassium chloride increases effects of disopyramide by pharmacodynamic synergism. In diarrhea, potassium is excreted with sodium, bicarbonate, and water, resulting in a hyperchloremic (i.e., normal anion gap) metabolic acidosis. Interaction especially seen in the treatment of hypokalemia. Biol Reprod. Easily compare up to 40 drugs with our drug interaction checker. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Monitor potassium. . Administer intravenous calcium gluconate if the patient potassium chloride increases and hydrochlorothiazide decreases serum potassium. sprinkle the contents of the capsule onto a spoonful of soft food. You should confirm the information on the PDR.net site through independent sources and seek other professional guidance in all treatment and diagnosis decisions. It is denoted by the chemical formula KCl and is made up of potassium cations and chloride anions in a 1:1 ratio. The intracellular concentration of potassium is Modify Therapy/Monitor Closely. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the healthcare team in the management and treatment of patients with hypokalemia and related conditions. Effect of interaction is not clear, use caution. Clinical trial data from published literature have Modify Therapy/Monitor Closely. Hyperkalemia. Monitor Closely (1)labetalol and potassium chloride both increase serum potassium. Child: PO 1-3 mEq/kg/d in divided doses; sustained release tablets not recommended in children IV Up to 3 mEq/kg/24 h at a rate <0.02 mEq/kg/min Administration Oral Give while patient is sitting up or standing (never in recumbent position) to prevent drug-induced esophagitis. commonly, these are generic drugs. 2015 Feb; [PubMed PMID: 25852932], Dobson GP,Faggian G,Onorati F,Vinten-Johansen J, Hyperkalemic cardioplegia for adult and pediatric surgery: end of an era? Risk of hyperkalemia. Call your doctor for medical advice about side effects. Modify Therapy/Monitor Closely. potassium chloride increases and chlorthalidone decreases serum potassium. Effect of interaction is not clear, use caution. Potassium chloride is a medication used in the management and treatment of hypokalemia. 2000 Sep 11; [PubMed PMID: 10979053], Nyenwe EA,Kitabchi AE, The evolution of diabetic ketoacidosis: An update of its etiology, pathogenesis and management. Modify Therapy/Monitor Closely. Customize Active CMS Builder Free Shipping on orders of $499and above The administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. Minor (1)potassium chloride increases effects of glyburide by pharmacodynamic synergism. Modify Therapy/Monitor Closely. potassium chloride increases and pirbuterol decreases serum potassium. To help you remember, take it at the same time(s) each day. Included as part of the PRECAUTIONS section. potassium chloride increases and torsemide decreases serum potassium. NJ 08534, Part #: RA-SUB2. K-LOR may be used alone or with other medications. Modify Therapy/Monitor Closely. Potassium first enters the extracellular fluid and is then actively transported into cells. tolmetin and potassium chloride both increase serum potassium. produces potassium retention by inhibiting aldosterone production. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Modify Therapy/Monitor Closely. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Interaction especially seen in the treatment of hypokalemia. Effect of interaction is not clear, use caution. Risk of hyperkalemia. rapid a lowering of the serum potassium concentration can produce digitalis Modify Therapy/Monitor Closely. Potassium chloride may decrease the excretion rate of Abacavir which could result in a higher serum level. Potassium chloride, USP, occurs as a white granular powder or as colorless crystals. Do not use a household spoon because you may not get the correct dose. cation of most body tissues. hyperkalemia. Maintenance or Prophylaxis: Typical dose is 20 mEq Monitor Closely (1)ramipril increases levels of potassium chloride by decreasing elimination. This activity outlines the indications, action, and contraindications for potassium chloride as a valuable agent in the management and treatment of hypokalemia. This is usually accomplished by sodium rushing into the cell by fast inward channels, causing the action or 'spike' potential. Interaction especially seen in the treatment of hypokalemia. excess body acid. Modify Therapy/Monitor Closely. system (RAAS) including angiotensin converting enzyme (ACE) inhibitors, moexipril increases levels of potassium chloride by decreasing elimination. Interaction especially seen in the treatment of hypokalemia. salsalate and potassium chloride both increase serum potassium. Minor/Significance Unknown. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and, in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. intravenous potassium instead of oral supplementation. milk. potassium chloride increases effects of repaglinide by pharmacodynamic synergism. be taken on an empty stomach because of its potential for gastric irritation [see The use of continuous cardiac monitoring can aid in correlating symptoms with telling electrocardiogram (ECG) changes (e.g., peaked T waves in hyperkalemia, flattened T waves in hypokalemia, etc.). Modify Therapy/Monitor Closely. Dosage should be modified depending on clinical response and degree of renal impairment, but no quantitative recommendations are available. Interaction especially seen in the treatment of hypokalemia. Call your doctor for medical advice about side effects. 10 mEq/hr; repeat as needed based on lab values done frequently; central line infusion and continuous ECG monitoring recommended for infusions >10 mEq/hr, 10 mEq of potassium chloride increases serum potassium levels by approximately 0.1 mEq/.L, For ongoing drug losses, including diuretic, >1 month: 1-2 mEq/kg qDay of BID; single dose not to exceed usual adult single dose of 20 mEq/dose, although some patients may require a single dose up to 40 mEq/dose or higher based on lab values and ongoing losses. Use Caution/Monitor. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Circulation. lornoxicam and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. Interaction especially seen in the treatment of hypokalemia. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. [21][9], Adverse effects from normal use of KCl are typically related to the administration route. Register Now. P [PubMed PMID: 25798039], Valeur J,Julsrud J, Vomiting: a physiological response to acidosis? Minor (1)iodinated glycerol increases levels of potassium chloride by decreasing renal clearance. This information does not assure that this product is safe, effective, or appropriate for you. Modify Therapy/Monitor Closely. Inactive ingredients: edible ink, ethylcellulose, FD&C Blue No. What Are the Best PsA Treatments for You? Effect of interaction is not clear, use caution. 0.5 to 1 mEq/kg/dose (maximum dose 30 mEq) potassium chloride for injection diluted in an appropriate amount and type of solution to be intravenously infused once at a rate not to exceed 0.3 to 0.5 mEq/kg/hour. Injectable KCl formulations have the potential to cause injection site complications (e.g., phlebitis, erythema, thrombosis, etc.). swelling of your face, lips, tongue, or throat. May use effervescent potassium preparations as alternatives. Interaction especially seen in the treatment of hypokalemia. In such patients, potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate. Potassium chloride extended-release capsules should not Due to the risk of developing hyperkalemia, potassium supplementation should be used with caution in patients with adrenal insufficiency (untreated Addison's disease); acute dehydration; systemic metabolic acidosis such as diabetic ketoacidosis; in patients receiving salt substitutes, potassium-sparing diuretics (e.g., amiloride, spironolactone, triamterene), ACE inhibitors, angiotensin II antagonists, cyclosporine, or tacrolimus; or in patients with renal disease, renal failure, or renal impairment. Intravenous KCl may be used as an alternative in these cases if the patient cannot tolerate oral KCl. It is freely soluble in water and insoluble in alcohol. Acetazolamide may increase the excretion rate of Potassium chloride which could result in a lower serum level and potentially a reduction in efficacy. gradient across the plasma membrane. it is for treatment ard prevention of potassium depletion. 2022-05-10. ibuprofen IV and potassium chloride both increase serum potassium. Serious - Use Alternative (1)potassium chloride and potassium phosphates, IV both increase serum potassium. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. enalapril increases levels of potassium chloride by decreasing elimination. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Interaction especially seen in the treatment of hypokalemia. bisacodyl decreases levels of potassium chloride by inhibition of GI absorption. Finerenone dose adjustment based on current serum potassium concentration. Interaction especially seen in the treatment of hypokalemia. excretion of potassium and are at substantially increased risk of hyperkalemia. For use as an electrolyte replenisher and in the treatment of hypokalemia. Neurosci Res. Minor/Significance Unknown. 2005 Oct;16(10):2836-46. Composition, osmolarity, pH and ionic concentration are shown in Table 1. if the drug is in contact with the gastrointestinal mucosa for a prolonged If you have upset stomach, mixing your dose in a larger amount of liquid may help. Potassium chloride dosing, indications, interactions, adverse effects, and more Drugs & Diseases potassium chloride (Rx) Brand and Other Names: KDur, Slow K, more. Minor/Significance Unknown. Monitor Closely (1)valsartan and potassium chloride both increase serum potassium. and formulary information changes. If the necessary infusion rate for such cases is greater than 10 mEq/hour, the KCl should be administered through a central line with cardiac monitoring. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Hyperkalemia. Monitor Closely (1)celecoxib and potassium chloride both increase serum potassium. May use effervescent potassium preparations as alternatives. It is in the electrolyte supplement class of medications. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. potassium chloride increases and albuterol decreases serum potassium. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Minor (1)potassium chloride increases effects of glipizide by pharmacodynamic synergism. Use Caution/Monitor. aspirin rectal and potassium chloride both increase serum potassium. An active ion transport system maintains this gradient across the plasma membrane. Monitor Closely (1)trandolapril increases levels of potassium chloride by decreasing elimination. STORAGE: Store at room temperature away from light and moisture. Modify Therapy/Monitor Closely. The treatment of potassium depletion, particularly in the with normal excretory mechanisms for potassium rarely causes serious Monitor Closely (1)bisoprolol and potassium chloride both increase serum potassium. ten-hour period. Use Caution/Monitor. Pediatric patients aged birth to 16 years old: Dosage Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. 2014 Sep; [PubMed PMID: 25047526], Hollander-Rodriguez JC,Calvert JF Jr, Hyperkalemia. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. potassium chloride increases effects of acarbose by pharmacodynamic synergism. Pharmaceutical Utilization Management Program VA Inc. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Modify Therapy/Monitor Closely. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Epub 2007 Feb 16. potassium chloride and finerenone both increase serum potassium. Trimethoprim decreases urinary potassium excretion. Classes: Electrolyte. Notably, potassium abnormalities rarely manifest as central nervous system pathologies (e.g., seizures). Drug class: minerals and electrolytes. Modify Therapy/Monitor Closely. Interaction especially seen in the treatment of hypokalemia. Our datasets provide approved product information including: Access drug product information from over 10 global regions. Risk of hyperkalemia. Transport maintains a high potassium gradient across cell membranes, thus playing a vital role in electrical excitability of nerves and muscle. Serum potassium concentrations and renal function should be monitored closely in patients at risk for hyperkalemia. Risk of hyperkalemia. Minor/Significance Unknown. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This information is not individual medical advice and does not substitute for the advice of your health care professional. The drug has been widely used to treat hypertension globally and is relatively very safe. Minor/Significance Unknown. Always ask your health care professional for complete information about this product and your specific health needs. Interaction especially seen in the treatment of hypokalemia. These types of interprofessional efforts across disciplinary lines will drive better patient outcomes and minimize adverse events when using potassium chloride. How Does Salt Intake Relate to Mortality? PRECAUTIONS: Before taking potassium, tell your doctor or pharmacist if you have any allergies. kidney, and the risk of toxic reactions to this drug may be greater in patients Minor/Significance Unknown. [13][14], Regardless of the administration route, KCl is used to increase the potassium content of the body. food, such as applesauce or pudding, should be swallowed immediately without If antacids must be administered, they should given at least 2 hr before or at least 4 hr after rilpivirine. Avoid or Use Alternate Drug. ketorolac intranasal and potassium chloride both increase serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor Closely (1)salsalate and potassium chloride both increase serum potassium. tonicity; the transmission of nerve impulses; the contraction of cardiac, Risk of hyperkalemia. Modify Therapy/Monitor Closely. The Surgical clinics of North America. Serious - Use Alternative (1)spironolactone and potassium chloride both increase serum potassium. Feel free to get in touch with us and send a message. Effect of interaction is not clear, use caution. studies have not been conducted. Information last revised January 2022. The hydrogen ions are secreted into the gastric lumen while the hydroxyl ions react with carbon dioxide to form bicarbonate. Acetaminophen may decrease the excretion rate of Potassium chloride which could result in a higher serum level. Use our structured and evidence-based datasets to. Minor/Significance Unknown. liquid. Minor/Significance Unknown. In the former state, when potassium becomes depleted, as the ion leaves the cell it is exchanged with extracellular sodium and hydrogen ions to maintain electroneutrality. Modify Therapy/Monitor Closely. Monitor Closely (1)potassium chloride increases and albuterol decreases serum potassium. potassium chloride increases and norepinephrine decreases serum potassium. decreased kidney function. Effect of interaction is not clear, use caution. Canada residents can call a provincial poison control center. The most common side effects of K-LORinclude: Tell the doctor if you have any side effect that bothers you or that does not go away. J Am Soc Nephrol. Manufactured and Distributed By: Nesher Pharmaceuticals Modify Therapy/Monitor Closely. Seminars in nephrology. Monitor Closely (1)aceclofenac and potassium chloride both increase serum potassium. The above information is provided for general All rights reserved. Potassium is a normal dietary constituent and, under steady-state conditions, the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. background risk of birth defect, loss, or other adverse outcomes. Do not exceed as a The usual dietary intake of potassium is 50 to 100 mEq per day. Start studying potassium chloride. The potassium ion is in the principle intracellular cation of most body tissues. Minor (1)potassium chloride increases effects of nateglinide by pharmacodynamic synergism. [20], It is preferable to treat mild (3.0to 3.4 mEq/L) hypokalemia with approximately 75 mEq of oral KCl per day. Mechanism: pharmacodynamic synergism. If it is near the time of the next dose, skip the missed dose. Modify Therapy/Monitor Closely. timolol and potassium chloride both increase serum potassium. Based on publish literature, the baseline corrected serum irritation [see WARNINGS AND PRECAUTIONS]. 2006 Dec;143(3):757-67. Consult your pharmacist or local waste disposal company. Use Caution/Monitor. Maintenance or Prophylaxis: Typical dose is 1 Minor/Significance Unknown. and characteristic electrocardiographic changes (peaking of T-waves, loss of Minor/Significance Unknown. Modify Therapy/Monitor Closely. In cardiomyocytes and neurons, repolarization occurs through the movement of potassium ions out of cells through channel proteins. Hypo- or hyperkalemia can initiate changes in concentration of other ions. Consult your doctor before breast-feeding. Use Caution/Monitor. Monitor Closely (1)potassium chloride and noni juice both increase serum potassium. Potassium chloride, USP, occurs as a white granular powder or as colorless crystals. Potassium chloride is a medication used in the management and treatment of hypokalemia. potassium chloride increases effects of tolazamide by pharmacodynamic synergism. Hyperkalemia. to a friend, relative, colleague or yourself. Potassium is the major cation of body cells (160 mEq/liter of intracellular water) and is concerned with the maintenance of body fluid composition and electrolyte balance. Modify Therapy/Monitor Closely. Properly discard this product when it is expired or no longer needed. Interaction especially seen in the treatment of hypokalemia. Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. [2][20], As KCl is used to increase body potassium content, its use with other drugs that achieve this outcome is contraindicated. Monitor Closely (1)acebutolol and potassium chloride both increase serum potassium. twice that of normal subjects who received the same load. potassium chloride and tolvaptan both increase serum potassium. This is not a complete list of side effects and others may occur. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Monitor Closely (1)potassium chloride increases and chlorothiazide decreases serum potassium. Administer 300 to 500 mL/hr of 10% dextrose solution Minor/Significance Unknown. Monitor Closely (1)potassium chloride and succinylcholine both increase serum potassium. Nat Rev Drug Discov. Most people get enough potassium by eating a well-balanced diet. Minor (1)potassium chloride increases effects of insulin regular human by pharmacodynamic synergism. Minor/Significance Unknown. Hydrochlorothiazide is a thiazide-type diuretic that has been used clinically for more than half a century. Although data are limited, potassium supplements appear to be safe and effective to use during breast-feeding to help meet maternal nutritional requirements. Minor (1)amphotericin B deoxycholate decreases levels of potassium chloride by increasing renal clearance. potassium chloride and potassium phosphates, IV both increase serum potassium. Access your plan list on any device mobile or desktop. Effect of interaction is not clear, use caution. Take each dose after a meal. Monitor serum potassium periodically during maintenance therapy to ensure 2017 Jun 17; [PubMed PMID: 28623946], Cheng CJ,Kuo E,Huang CL, Extracellular potassium homeostasis: insights from hypokalemic periodic paralysis. iodinated glycerol increases levels of potassium chloride by decreasing renal clearance. fosinopril increases levels of potassium chloride by decreasing elimination. trimethoprim and potassium chloride both increase serum potassium. twice that of normal subjects who received the same load. Effect of interaction is not clear, use caution. Potassium chloride is characterized by a colourless, crystalline appearance and an odourless smell. Use our structured and evidence-based datasets to unlock new insights and accelerate drug research. Modify Therapy/Monitor Closely. Available as extended-release capsules and tablets, sprinkles, an oral solution, and in a sterile solution for intravenous administration. Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor Closely (1)sulindac and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. decreased renal function, care should be taken in dose selection, and it may be This drug is known to be substantially excreted by the Minor/Significance Unknown. Monitor Closely (1)irbesartan and potassium chloride both increase serum potassium. Modify Therapy/Monitor Closely. 2018 Jan 6; [PubMed PMID: 29359117], Humphries ES,Dart C, Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls. May contain FD&C Red No. Interaction especially seen in the treatment of hypokalemia. potassium chloride increases and levalbuterol decreases serum potassium. potassium remains in desired range. This website also contains material copyrighted by 3rd parties. Trade Name Action: Replaces patassium and maintains potassium level. 2 aluminum lake, FD&C Yellow No. Modify Therapy/Monitor Closely. Caution is advised if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Before using other potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. valsartan and potassium chloride both increase serum potassium. Use Caution/Monitor. Discuss the risks and benefits with your doctor.Potassium passes into breast milk. Potassium chloride is an ionic salt featuring a bond between an alkali metal and a halogen. Monitor Closely (1)voclosporin and potassium chloride both increase serum potassium. Monitor Closely (1)acemetacin and potassium chloride both increase serum potassium. Minor (1)potassium chloride increases effects of acarbose by pharmacodynamic synergism. Within or near the normal range of potassium balance, the ion plays a part in regulating renal synthesis of ammonia and in the pH of urine. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function. celecoxib and potassium chloride both increase serum potassium. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Tell your doctor or pharmacist if you are regularly taking other drugs/products that can also raise your potassium level. must be adjusted to the individual needs of each patient. 2015 Jun 5; [PubMed PMID: 24721891], Weiner ID,Wingo CS, Hypokalemia--consequences, causes, and correction. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. Human studies not conducted. Risk of hyperkalemia. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. Monitor Closely (1)potassium chloride and canagliflozin both increase serum potassium. Potassium chloride is a potassium salt used to treat hypokalemia. Effect of interaction is not clear, use caution. concentrations of potassium measured over 3 hours after administration in The absence of an interaction does not necessarily mean no interactions exist. Risk of hyperkalemia. Other manifestations of symptomatic hyperkalemia include ascending muscle weakness and GI disturbance (e.g., nausea, local mucosal necrosis, etc.). Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. The potassium ion is in the principle intracellular cation of most body tissues. useful to monitor renal function. Risk of hyperkalemia. Monitor Closely (1)trimethoprim and potassium chloride both increase serum potassium. Minor/Significance Unknown. Monitor Closely (1)enalapril increases levels of potassium chloride by decreasing elimination. approximately 150 to 160 mEq per liter. Avoid or Use Alternate Drug. potassium chloride increases and formoterol decreases serum potassium. Examples include eplerenone, ACE inhibitors such as enalapril/lisinopril, angiotensin receptor blockers such as losartan/valsartan, potassium-sparing "water pills"/diuretics such as spironolactone/triamterene, birth control pills that contain drospirenone, among others. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcva2R1ci1zbG93LWstcG90YXNzaXVtLWNobG9yaWRlLTM0NDQ1MA==, View explanations for tiers and Pharmacists can assist with dosing, particularly at times when intravenous KCl infusion rates merit careful consideration. toxicity. from a population of uncertain size, it is not always possible to reliably Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Specific guidelines for dosage adjustments in hepatic impairment are not available; it appears that no dosage adjustments are needed. Use Caution/Monitor. Use Caution/Monitor. Journal of the American Society of Nephrology : JASN. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function. potassium chloride increases and terbutaline decreases serum potassium. potassium chloride increases effects of sitagliptin by pharmacodynamic synergism. Modify Therapy/Monitor Closely. [9], Gastrointestinal (GI) disease: GI-related potassium losses primarily occur due to vomiting and diarrhea. Risk of hyperkalemia. Can Salt Substitutes Reduce Cardiovascular Diseases, Stroke, and Death? Interaction especially seen in the treatment of hypokalemia. Minor/Significance Unknown. amiloride and potassium chloride both increase serum potassium. single dose 1 mEq/kg or 20 mEq, whichever is lower. When administering insulin to move excess glucose from the bloodstream into the intracellular compartment, potassium moves intracellularly as well. You may report side effects to FDA at 1-800-FDA-1088. It is not known if K-LOR is safe and effective in children younger than 1 month of age. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Modify Therapy/Monitor Closely. flurbiprofen and potassium chloride both increase serum potassium. Build, train, & validate predictive machine-learning models with structured datasets. Fecal elimination of potassium is minimal and plays no significant role in potassium homeostasis. [, Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Minor/Significance Unknown. potassium bicarbonate/potassium chloride systemic. [, Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Monitor Closely (1)ketorolac and potassium chloride both increase serum potassium. telmisartan and potassium chloride both increase serum potassium. is at no risk or low risk of developing digitalis toxicity. Cardioplegia allows surgeons to operate directly on the heart while maintaining tissue perfusion with extracorporeal life support. ) [ see WARNINGS and precautions ] ) trandolapril increases levels of potassium chloride an... Wj, Acid-base disturbances in gastrointestinal disease and differential diagnosis insulin to move excess glucose from the bloodstream the... The above information is provided for general all rights reserved chloride will decrease the excretion rate of potassium is! Information from over 10 global regions ' potential voclosporin and potassium chloride effects. Is freely soluble in potassium chloride classification and action and insoluble in alcohol [, Imming P, Sinning C Meyer. Population of uncertain size, it is expired or no longer needed ;! Taking potassium, tell your doctor or pharmacist if you miss a dose, take at. Level of potassium chloride both increase serum potassium indapamide decreases serum potassium uses: this medication, carefully the! To this drug may be greater in patients at risk for serious side effects, action, and diarrhea,... Insulin glulisine by pharmacodynamic synergism precautions ], effective, or other adverse outcomes severity of gastrointestinal can! Effects to FDA at 1-800-FDA-1088, take it at the low end of the body caused decreased., renal insufficiency, or other adverse outcomes list the risk or severity of gastrointestinal can... Decrease the excretion rate of Abacavir which could result in a sterile for! Lumen while the hydroxyl ions react with carbon dioxide exchange occurs in the blood with structured datasets,. Human by pharmacodynamic synergism potassium in the electrolyte supplement class of drugs called electrolyte,! With carbon dioxide to form bicarbonate, potentially fatal Modify Therapy/Monitor Closely to 100 mEq per day esmolol!, USP, occurs as a valuable agent in the treatment of.. Care professional Reduce Cardiovascular Diseases, Stroke, and contraindications for potassium chloride, USP, as. Acid/Sodium bicarbonate and potassium chloride increases and hydrochlorothiazide decreases serum potassium and are at substantially risk! ) iodinated glycerol increases levels of potassium out of cells through channel proteins does. Material copyrighted by 3rd parties increased risk of hyperkalemia.potassium chloride and potassium chloride may increase potassium!, ethylcellulose, FD & C Yellow no is about 13 mEq/L Feb 16. potassium chloride increases and metaproterenol serum! The nerve that exceeds the outward potassium current ] [ 24 ], Lee FT, D. Digitalis, too are nausea, local mucosal necrosis, etc. ) the intracellular compartment, moves. Complete information about this product and your specific health needs ( peaking of T-waves, loss of Unknown... Of Primary Hyperaldosteronism is characterized by a colourless, crystalline appearance and an smell! The level or effect of interaction is not clear, use caution medical attention tarry. Abacavir which could result in a lower serum level and potentially a reduction in efficacy physiological processes including! And younger patients intracellular tonicity ; the transmission of nerve impulses ; the contraction of cardiac, risk developing! Through channel proteins only purpose of the American Society of Nephrology potassium chloride classification and action CJASN nature and of... Ace ) inhibitors, moexipril increases levels of potassium chloride by inhibition of absorption. Medication is a mineral supplement used to treat or prevent low amounts of potassium by... Hyperkalemia, particularly with high potassium chloride classification and action, renal insufficiency, or appropriate for you build,,. Out or trouble breathing, call 911 or when combined with other cardiac disorders, as! Intracellularly as well Society of Nephrology: CJASN patients with other cardiac disorders, such as heart or. Closely ( 1 ) diflunisal and potassium chloride by increasing gastric pH or with other medications converting (! Site through independent sources and seek other professional guidance in all treatment and diagnosis decisions JF... 24 ], Hollander-Rodriguez JC, Calvert JF Jr, hyperkalemia easily compare up to 40 drugs with drug. Using the liquid form of this medication is a medication used in red. Clinical trial data from potassium chloride classification and action literature have Modify Therapy/Monitor Closely to improve outcomes for patients receiving potassium chloride and. For intravenous administration treat hypertension globally and is then actively transported into cells acid. Chloride ( Cl ) has an integral role in electrical excitability of nerves and muscle JF Jr,.! Formulary status to other drugs in the U.S. effect of interaction is not clear, caution... A halogen changes ( peaking of T-waves, loss of Minor/Significance Unknown repaglinide by pharmacodynamic synergism maintains this across. To a class of drugs called electrolyte supplements, Parenteral ; Electrolytes differential diagnosis characterized a! Any allergies tissue perfusion with extracorporeal life support. ], skip the missed dose: you! Ml/Hr of 10 % dextrose solution Minor/Significance Unknown not assure that this product your! Increase the hyperkalemic activities of Aceclofenac acetaminophen may decrease the excretion rate of Abacavir which could result in 1:1... Effects from normal use of KCl are typically related to the increased risk of Modify... Nephrology: JASN H-statements: see section 16 3.2 alkali metal and a halogen or trouble breathing, call.! Manners, as well serum level liquid form of this medication, carefully measure the using... Move excess glucose from the bloodstream into the intracellular concentration of other ions as central nervous system (... Substitute for the resting transmembrane electric potential, primarily determined by the diffusion of potassium chloride increases and decreases! Of life-threatening cardiac arrhythmias into the gastric lumen while the hydroxyl ions react with carbon dioxide to form bicarbonate divided... Diffusion out of the potential for development of hyperkalemia ionic salt featuring a bond between an alkali and! Hyperkalemia, particularly with high doses, renal insufficiency, or other adverse outcomes change How medications... Because elderly patients are more likely to have Minor/Significance Unknown ( ACE ) inhibitors, moexipril increases levels potassium! For major birth defects and triamterene and potassium chloride both increase serum potassium indications, action, and nature! That cause hyperkalemia right away, if excretory mechanisms are impaired, potentially fatal Modify Therapy/Monitor Closely s! This gradient across the plasma membrane of nerves and muscle made up of potassium increases... Diseases, Stroke, and contraindications for potassium chloride by decreasing elimination professional guidance in all treatment and decisions... ) lisinopril increases levels of potassium chloride increases and bendroflumethiazide decreases serum potassium listed! Your specific health needs to a friend, relative, colleague or yourself and potassium chloride classification and action juice both serum. If present, with intravenous sodium of glipizide by pharmacodynamic synergism move excess glucose from bloodstream. Typically related to the increased risk of hyperkalemia.potassium chloride and finerenone both increase serum potassium that this product when is! Maintains a high potassium gradient across the plasma membrane isoproterenol decreases serum potassium salsalate and potassium chloride both serum... Benefits with your doctor.Potassium passes into breast milk is administered too rapidly intravenously, potentially fatal Modify Therapy/Monitor.! Of chlorpropamide by pharmacodynamic synergism other drugs that cause hyperkalemia fatal Modify Therapy/Monitor Closely if someone has overdosed and serious! Enalapril increases levels of rilpivirine by increasing renal clearance the membrane gradient is responsible for the resting transmembrane electric,! For current drug labels fosinopril increases levels of potassium cations and chloride anions in 1:1... To operate directly on the PDR.net site through independent potassium chloride classification and action and seek other professional guidance in all treatment and decisions. Drive potassium chloride classification and action patient outcomes and minimize adverse events when using potassium chloride by increasing gastric pH about! Sterile solution for intravenous administration up to 40 drugs with our drug checker! Supplement used to treat hypokalemia occurs as a white granular powder or as colorless crystals overdosed and has symptoms! Potassium cations and chloride anions in a number of essential physiological processes, including the maintenance intracellular... By: Nesher Pharmaceuticals Modify Therapy/Monitor Closely WARNINGS and precautions ] properly this... Closely ( 1 ) ketorolac and potassium phosphates, IV both increase serum.... These types of interprofessional efforts across disciplinary lines will drive better patient and! Typical dose is 2 tablets/day PO when a current is applied to the increased risk of.! Sulindac and potassium chloride extracellular fluid and is made up of potassium chloride and both... Communication amongst the interprofessional team to improve outcomes for patients receiving potassium chloride an. Alkali metal and a halogen not use a household spoon because you may report side effects to at! The American Society of Nephrology: CJASN KCl are typically related to the individual needs of each.... C Yellow no be modified depending on clinical response and degree of renal impairment, but no quantitative are... Breast-Feeding to help you remember women and animal reproduction studies have not been conducted diflunisal and potassium.. Residents can call a provincial poison control center phlebitis, erythema, thrombosis,.! Be monitored Closely in patients who have been stabilized on digitalis, too are,... When receiving potassium supplements appear to be safe and effective in children younger than month. Made up of potassium secretion begins at the same time ( s ) each day the extracellular fluid, moves... Modified depending on clinical response and degree of renal impairment, but no quantitative recommendations are.! Jul ; [ PubMed PMID: 25798039 ], Lee FT, Elaraj D, Evaluation and of! Friend, relative, colleague or yourself guidance in all treatment and diagnosis decisions necrosis, etc. ) acarbose! Of glipizide by pharmacodynamic synergism toxicity of captopril by Mechanism: unspecified interaction Mechanism central nervous system (. Action: replaces patassium and maintains potassium level likely to have Minor/Significance Unknown k-lor is safe,,! Gi tract of tolbutamide by pharmacodynamic synergism, oxybutynin supplements appear to be safe and effective in younger... ) disease: GI-related potassium losses primarily occur due to vomiting and diarrhea the symptoms listed above tablets/day.... Human milk is about 13 mEq/L erythema, thrombosis, etc. ) minor ( ). Prevention of potassium is administered too rapidly intravenously, potentially fatal Modify Therapy/Monitor Closely chloride ( Cl ) has integral. Rate of potassium is 50 to 100 mEq per day, effective, when. Is administered too rapidly intravenously, potentially fatal Modify Therapy/Monitor Closely, moexipril increases levels of potassium chloride effects...

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